Foxp3 and BATF cooperatively direct cis-regulatory programs and gene expression for effector Treg cell differentiation [ChIP-Seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 34 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 34 samples: 34 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Foxp3 and BATF cooperatively direct cis-regulatory programs and gene expression for effector Treg cell differentiationImmunity · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE267882_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1113592 and SRA study SRP508697. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 34 sample titles: 34 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8281045 WT_Treg_1 (BATF ChIP-seq)
- GSM8281046 WT_Treg_2 (BATF ChIP-seq)
- GSM8281047 WT_Tconv_1 (BATF ChIP-seq)
- GSM8281048 WT_Tconv_2 (BATF ChIP-seq)
- GSM8281049 WT_Treg (BATF ChIP-seq input)
- GSM8281050 WT_Tconv (BATF ChIP-seq input)
- GSM8281051 WT_Treg_1 (Foxp3 ChIP-seq)
- GSM8281052 WT_Treg_2 (Foxp3 ChIP-seq)
- GSM8281053 BATFKO_Treg_1 (Foxp3 ChIP-seq)
- GSM8281054 BATFKO_Treg_2 (Foxp3 ChIP-seq)
- GSM8281055 WT_cTreg_1 (Foxp3 ChIP-seq)
- GSM8281056 WT_cTreg_2 (Foxp3 ChIP-seq)
- GSM8281057 WT_eTreg_1 (Foxp3 ChIP-seq)
- GSM8281058 WT_eTreg_2 (Foxp3 ChIP-seq)
- GSM8281059 WT_Treg (Foxp3 ChIP-seq input)
- GSM8281060 BATFKO_Treg (Foxp3 ChIP-seq input)
- GSM8281061 WT_cTreg_1 (Foxp3 ChIP-seq input)
- GSM8281062 WT_cTreg_2 (Foxp3 ChIP-seq input)
- GSM8281063 WT_eTreg_1 (Foxp3 ChIP-seq input)
- GSM8281064 WT_eTreg_2 (Foxp3 ChIP-seq input)
- GSM9204512 WT_Treg_3 (BATF ChIP-seq) (R397W_Treg_control)
- GSM9204513 WT_Treg_4 (BATF ChIP-seq) (R397W_Treg_control)
- GSM9204514 R397W_Treg_1 (BATF ChIP-seq)
- GSM9204515 R397W_Treg_2 (BATF ChIP-seq)
- GSM9204516 WT_Treg (BATF ChIP-seq input) (R397W_Treg_control)
- GSM9204517 R397W_Treg (BATF ChIP-seq input)
- GSM9204518 WT_Treg_1 (IRF4 ChIP-seq)
- GSM9204519 WT_Treg_2 (IRF4 ChIP-seq)
- GSM9204520 WT_Treg_3 (IRF4 ChIP-seq)
- GSM9204521 WT_Treg_4 (IRF4 ChIP-seq)
- GSM9204522 WT_Tconv_1 (IRF4 ChIP-seq)
- GSM9204523 WT_Tconv_2 (IRF4 ChIP-seq)
- GSM9204524 WT_Tconv_3 (IRF4 ChIP-seq)
- GSM9204525 WT_Tconv_4 (IRF4 ChIP-seq)
- GSE267881 Foxp3 and BATF cooperatively direct cis-regulatory programs and gene expression for effector Treg cell differentiation [ATAC-Seq] 30 samples shares foxp3, batf, cis-regulatory, cooperatively, programs, effector, direct
- GSE267884 Foxp3 and BATF cooperatively direct cis-regulatory programs and gene expression for effector Treg cell differentiation [scMultiome] 16 samples shares foxp3, batf, cis-regulatory, cooperatively, programs, effector, direct
- GSE267967 Foxp3 and BATF cooperatively direct cis-regulatory programs and gene expression for functional differentiation of Treg cells [RNA-seq] 26 samples shares foxp3, batf, cis-regulatory, cooperatively, programs, direct
- GSE281499 The transcription factor BATF pioneers the differentiation program of cytolytic effector CD8+ T cells through the direct interaction with IRF4 (CUT&RUN) 50 samples shares batf, effector, direct
- GSE281498 The transcription factor BATF pioneers the differentiation program of cytolytic effector CD8+ T cells through the direct interaction with IRF4 (ATAC-seq) 20 samples shares batf, effector, direct
- GSE305064 FOXP3 Expression Depends on Cell-Type Specific Cis-Regulatory Element and Transcription Factor Circuitry [mouse_Tconv_ChIP-seq] 15 samples shares foxp3, cis-regulatory, chip-seq
- GSE281500 The transcription factor BATF pioneers the differentiation program of cytolytic effector CD8+ T cells through the direct interaction with IRF4 (RNA-seq) 10 samples shares batf, effector, direct
- GSE268623 Dynamic Foxp3-chromatin interaction controls tunable Treg cell function [Cut&Run Foxp3 Batf Ets1] 24 samples shares foxp3, batf
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.