GEO series
Escape from X inactivation is directly modulated by Xist non-coding RNA [multiclone]
GSE259397
Mus musculus
Expression profiling by high throughput sequencing
21 samples
2025/12/09
GPL24247
Summary
X-chromosome inactivation silences one copy of the X-chromosome in female cells, but a number of genes escapes this inactivation. We asked whether increased levels of Xist RNA, the molecular actor driving X-inactivation, impacts expression levels of escapees. To this end, we performed transcriptomic profiling of X-linked gene expression in clonal neural progenitor cell lines with varying Xist levels.
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Paper (PMID 41398052) ↗
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