Body mass index alone may not serve as a reliable indicator of the risk of developing rheumatoid arthritis
RNA-seq (gene expression) · mouse · 11 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 11 samples: 11 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Incidence of collagen-induced arthritis is elevated by a high-fat diet without influencing body weight in miceRMD open · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE260460_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1081810 and SRA study SRP492302. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 11 sample titles: 11 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8117692 DBA_CIA_a
- GSM8117693 DBA_CIA_b
- GSM8117694 DBA_CIA_c
- GSM8117695 DBA_Sham_a
- GSM8117696 DBA_Sham_b
- GSM8117697 DBA_Sham_c
- GSM8117698 HFDBA_CIA_a
- GSM8117699 HFDBA_CIA_b
- GSM8117700 HFDBA_CIA_c
- GSM8117701 HFDBA_Sham_a
- GSM8117702 HFDBA_Sham_b
- GSE273883 CX3CR1+ Synovial Macrophages for Barrier Restore in Rheumatoid Arthritis: A New Target for Mesenchymal Stem Cell-Based Therapy? 35 samples shares rheumatoid, arthritis
- GSE234595 TH17 cells converted into exTH17 cells sustain rheumatoid-like IL-17–independent inflammatory arthritis 16 samples shares rheumatoid, arthritis
- GSE318778 Ligature-induced periodontitis in mice potentially accelerates CD4+ T cells senescence and exacerbates rheumatoid arthritis 12 samples shares rheumatoid, arthritis
- GSE271058 Effectiveness of low-intensity exercise in mitigating active arthritis exacerbation in a mouse rheumatoid-arthritis model 12 samples shares rheumatoid, arthritis
- GSE241929 Hyperactive lateral habenula mediates the comorbidity between rheumatoid arthritis and depression-like behaviors 11 samples shares rheumatoid, arthritis
- GSE267630 ST36 acupuncture ameliorates immune cell proliferation and polarization by inhibiting sympathetic activity in rheumatoid arthritis 10 samples shares rheumatoid, arthritis
- GSE292043 A conserved differentiation program facilitates inhibitory neuron production in the developing mouse and human cerebellum 24 samples shares developing, serve
- GSE234597 TH17 cells converted into exTH17 cells sustain rheumatoid-like IL-17–independent inflammatory arthritis 21 samples shares rheumatoid, arthritis
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.