ST36 acupuncture ameliorates immune cell proliferation and polarization by inhibiting sympathetic activity in rheumatoid arthritis
RNA-seq (gene expression) · mouse · 10 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 10 samples: 10 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE267630_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1112165 and SRA study SRP508302. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 10 sample titles: 10 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8271217 lymph node, Control, Day15 (C_15)
- GSM8271218 lymph node, Control, Day15 (C_16)
- GSM8271219 lymph node, Control, Day15 (C_17)
- GSM8271220 lymph node, AIA, Day15 (M_10)
- GSM8271221 lymph node, AIA, Day15 (M_31)
- GSM8271222 lymph node, AIA, Day15 (M_38)
- GSM8271223 lymph node, AIA, Day15 (M_5)
- GSM8271224 lymph node, Acu, Day15 (Z_6)
- GSM8271225 lymph node, Acu, Day15 (Z_28)
- GSM8271226 lymph node, Acu, Day15 (Z_4)
- GSE342059 Microfluidic Co-Encapsulation of Exosomal miRNAs and Antioxidant Enzymes Ameliorates Hepatic Steatosis by Driving M2 Polarization and Reparative Neutrophil Recruitment 26 samples shares polarization, ameliorates
- GSE266962 Targeting Immunoproteasome in Macrophages Suppresses M1 Polarization and Ameliorates Experimental Emphysema via Activating NRF1 and NRF2-P62 Axis 24 samples shares polarization, ameliorates
- GSE303021 Hdac11 promotes idiopathic pulmonary fibrosis through macrophage M2-type polarization and myofibroblast differentiation by inhibiting Parkin-dependent mitophagy 13 samples shares polarization, inhibiting
- GSE309379 Nucleophosmin supports WNT-driven hyperproliferation and tumour initiation 111 samples shares proliferation
- GSE296763 Mitochondrial respiration is necessary for CD8 T cell proliferation and cell fate 99 samples shares proliferation
- GSE285141 Histone H3.3 ensures cell proliferation and genomic stability during myeloid cell development [RNA-seq] 81 samples shares proliferation
- GSE293228 Compartment size and proliferation shape the murine T cell receptor repertoire in splenic T- and B cell zones during an immune response 72 samples shares proliferation
- GSE269239 Mitochondrial respiration in microglia is essential for response to demyelinating injury but not proliferation 64 samples shares proliferation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.