RNA-seq Analysis of Acute myeloid leukemia (AML) primary samples
RNA-seq (gene expression) · human · 69 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Acute myeloid leukemiaThis series is part of our curated briefing on it.
- Samples
- 69 samples: 69 × RNA-SeqofAML primary sample of patientGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Synergistic potential of CDK4/6 inhibitors and ATRA in non-APL AMLBritish journal of haematology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE260773_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1083463 and SRA study SRP493182. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 69 samples.
How we read this: 1 replicated groups read from 69 sample titles; they account for 69 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8124239 RNA-SeqofAML primary sample of patient 1 RNA-SeqofAML primary sa…
- GSM8124240 RNA-SeqofAML primary sample of patient 2 RNA-SeqofAML primary sa…
- GSM8124241 RNA-SeqofAML primary sample of patient 3 RNA-SeqofAML primary sa…
- GSM8124242 RNA-SeqofAML primary sample of patient 4 RNA-SeqofAML primary sa…
- GSM8124243 RNA-SeqofAML primary sample of patient 5 RNA-SeqofAML primary sa…
- GSM8124244 RNA-SeqofAML primary sample of patient 6 RNA-SeqofAML primary sa…
- GSM8124245 RNA-SeqofAML primary sample of patient 7 RNA-SeqofAML primary sa…
- GSM8124246 RNA-SeqofAML primary sample of patient 8 RNA-SeqofAML primary sa…
- GSM8124247 RNA-SeqofAML primary sample of patient 9 RNA-SeqofAML primary sa…
- GSM8124248 RNA-SeqofAML primary sample of patient 10 RNA-SeqofAML primary sa…
- GSM8124249 RNA-SeqofAML primary sample of patient 11 RNA-SeqofAML primary sa…
- GSM8124250 RNA-SeqofAML primary sample of patient 12 RNA-SeqofAML primary sa…
- GSM8124251 RNA-SeqofAML primary sample of patient 13 RNA-SeqofAML primary sa…
- GSM8124252 RNA-SeqofAML primary sample of patient 14 RNA-SeqofAML primary sa…
- GSM8124253 RNA-SeqofAML primary sample of patient 15 RNA-SeqofAML primary sa…
- GSM8124254 RNA-SeqofAML primary sample of patient 16 RNA-SeqofAML primary sa…
- GSM8124255 RNA-SeqofAML primary sample of patient 17 RNA-SeqofAML primary sa…
- GSM8124256 RNA-SeqofAML primary sample of patient 18 RNA-SeqofAML primary sa…
- GSM8124257 RNA-SeqofAML primary sample of patient 19 RNA-SeqofAML primary sa…
- GSM8124258 RNA-SeqofAML primary sample of patient 20 RNA-SeqofAML primary sa…
- GSM8124259 RNA-SeqofAML primary sample of patient 21 RNA-SeqofAML primary sa…
- GSM8124260 RNA-SeqofAML primary sample of patient 22 RNA-SeqofAML primary sa…
- GSM8124261 RNA-SeqofAML primary sample of patient 23 RNA-SeqofAML primary sa…
- GSM8124262 RNA-SeqofAML primary sample of patient 24 RNA-SeqofAML primary sa…
- GSM8124263 RNA-SeqofAML primary sample of patient 25 RNA-SeqofAML primary sa…
- GSM8124264 RNA-SeqofAML primary sample of patient 26 RNA-SeqofAML primary sa…
- GSM8124265 RNA-SeqofAML primary sample of patient 27 RNA-SeqofAML primary sa…
- GSM8124266 RNA-SeqofAML primary sample of patient 28 RNA-SeqofAML primary sa…
- GSM8124267 RNA-SeqofAML primary sample of patient 29 RNA-SeqofAML primary sa…
- GSM8124268 RNA-SeqofAML primary sample of patient 31 RNA-SeqofAML primary sa…
- GSM8124269 RNA-SeqofAML primary sample of patient 32 RNA-SeqofAML primary sa…
- GSM8124270 RNA-SeqofAML primary sample of patient 33 RNA-SeqofAML primary sa…
- GSM8124271 RNA-SeqofAML primary sample of patient 34 RNA-SeqofAML primary sa…
- GSM8124272 RNA-SeqofAML primary sample of patient 35 RNA-SeqofAML primary sa…
- GSM8124273 RNA-SeqofAML primary sample of patient 36 RNA-SeqofAML primary sa…
- GSM8124274 RNA-SeqofAML primary sample of patient 37 RNA-SeqofAML primary sa…
- GSM8124275 RNA-SeqofAML primary sample of patient 38 RNA-SeqofAML primary sa…
- GSM8124276 RNA-SeqofAML primary sample of patient 39 RNA-SeqofAML primary sa…
- GSM8124277 RNA-SeqofAML primary sample of patient 40 RNA-SeqofAML primary sa…
- GSM8124278 RNA-SeqofAML primary sample of patient 41 RNA-SeqofAML primary sa…
+ 29 more — browse all 69 samples with per-sample file links →
- GSE137851 The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia 387 samples same disease briefing · shares leukemia, myeloid, acute
- GSE270185 Repurposing CD19-directed immunotherapies for pediatric t(8;21) acute myeloid leukemia 249 samples same disease briefing · shares leukemia, myeloid, acute
- GSE303795 Halofuginone exerts broad-spectrum cytotoxic effects by regulating p-eIF2α-S100A8/A9-calcium signaling, inhibiting global protein synthesis, and reversing the resistance of idarubicin in acute myeloid leukemia 6 samples same disease briefing · shares leukemia, myeloid, acute
- GSE137574 Kevetrin induces apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells 24 samples same disease briefing · shares leukemia, myeloid, acute
- GSE122515 Bonn Dataset 3 of meta-analysis on AML classification, RNAseq dataset 0 samples same disease briefing · shares aml
- GSE129437 Genome-wde mapping of BRD9 binding sites and gene expression changes upon BRD9 knockdown 6 samples same disease briefing
- GSE272681 The cellular hierarchy of acute myeloid leukemia informs personalized treatment 108 samples shares leukemia, myeloid, acute
- GSE306605 Venetoclax Enhances gamma-deltaT cell Antileukemia Activity via Fatty Acid Oxidation in Relapsed Acute Myeloid Leukemia 6 samples shares leukemia, myeloid, acute
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.