Gene expression and Epigenome analysis of hESCs undergoing neuronal differentiation
DNA methylation · human · 194 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Homo sapiens (human)
- Samples
- 194 samples: 121 distinct titles, 16 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Citalopram exposure of hESCs during neuronal differentiation identifies dysregulated genes involved in neurodevelopment and depressionFrontiers in cell and developmental biology · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE260892_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA1083914. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 194 sample titles: 121 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8127438 HS360-Day10-RNA-seq-rep1
- GSM8127439 HS360-Day10-RNA-seq-rep2
- GSM8127440 HS360-Day10-RNA-seq-rep3
- GSM8127441 HS360-Day10-CIT50-RNA-seq-rep1
- GSM8127442 HS360-Day10-CIT50-RNA-seq-rep2
- GSM8127443 HS360-Day10-CIT50-RNA-seq-rep3
- GSM8127444 HS360-Day10-CIT50-RNA-seq-rep4
- GSM8127445 HS360-Day10-CIT100-RNA-seq-rep1
- GSM8127446 HS360-Day10-CIT100-RNA-seq-rep2
- GSM8127447 HS360-Day10-CIT100-RNA-seq-rep3
- GSM8127448 HS360-Day10-CIT200-RNA-seq-rep1
- GSM8127449 HS360-Day10-CIT200-RNA-seq-rep2
- GSM8127450 HS360-Day10-CIT200-RNA-seq-rep3
- GSM8127451 HS360-Day10-CIT400-RNA-seq-rep1
- GSM8127452 HS360-Day10-CIT400-RNA-seq-rep2
- GSM8127453 HS360-Day10-CIT400-RNA-seq-rep3
- GSM8127454 HS360-Day10-CIT400-RNA-seq-rep4
- GSM8127455 HS360-Day10-RNA-seq-rep4
- GSM8127456 HS360-Day10-RNA-seq-rep5
- GSM8127457 HS360-Day10-RNA-seq-rep6
- GSM8127458 HS360-Day10-CIT50-RNA-seq-rep5
- GSM8127459 HS360-Day10-CIT50-RNA-seq-rep6
- GSM8127460 HS360-Day10-CIT100-RNA-seq-rep4
- GSM8127461 HS360-Day10-CIT100-RNA-seq-rep5
- GSM8127462 HS360-Day10-CIT200-RNA-seq-rep4
- GSM8127463 HS360-Day10-CIT200-RNA-seq-rep5
- GSM8127464 HS360-Day10-CIT400-RNA-seq-rep5
- GSM8127465 HS360-Day10-CIT400-RNA-seq-rep6
- GSM8127466 HS360-Day13-RNA-seq-rep1
- GSM8127467 HS360-Day13-RNA-seq-rep2
- GSM8127468 HS360-Day13-RNA-seq-rep3
- GSM8127469 HS360-Day13-CIT50-RNA-seq-rep1
- GSM8127470 HS360-Day13-CIT50-RNA-seq-rep2
- GSM8127471 HS360-Day13-CIT50-RNA-seq-rep3
- GSM8127472 HS360-Day13-CIT50-RNA-seq-rep4
- GSM8127473 HS360-Day13-RNA-seq-rep4
- GSM8127474 HS360-Day13-RNA-seq-rep5
- GSM8127475 HS360-Day13-RNA-seq-rep6
- GSM8127476 HS360-Day13-CIT50-RNA-seq-rep5
- GSM8127477 HS360-Day13-CIT50-RNA-seq-rep6
+ 154 more — browse all 194 samples with per-sample file links →
- GSE260888 Gene expression analysis of hESCs undergoing neuronal differentiation exposed to citalopram 89 samples shares undergoing, neuronal, hescs
- GSE260889 Single cell gene expression analysis of hESCs undergoing neuronal differentiation 16 samples shares undergoing, neuronal, hescs
- GSE301239 SETBP1 variants outside the degron disrupt DNA-binding, transcription and neuronal differentiation capacity to cause a heterogeneous neurodevelopmental disorder [induced neurons] 51 samples shares neuronal
- GSE244435 Engrailed 1 deficiency induces changes in ciliogenesis during human neuronal differentiation 48 samples shares neuronal
- GSE294150 Comprehensive analysis of gene expression in visceral fat of morbidly obese patients undergoing bariatric surgery [Human] 40 samples shares undergoing
- GSE244655 Long read subcellular fractionation and sequencing reveals the translational fate of full length mRNA isoforms during neuronal differentiation 40 samples shares neuronal
- GSE149407 Single-Cell Multi-Omics Sequencing Reveals the Dynamic Epigenome Landscape of Human Adult Spermatogenesis 1435 samples shares epigenome
- GSE245323 Dynamics and consequences of widespread transcript isoform changes during neuronal differentiation [RNA-Seq] 24 samples shares neuronal
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.