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Small-Molecule-Induced ERBB4 Activation to Treat Heart Failure

GSE261219 Homo sapiens Expression profiling by high throughput sequencing 9 samples Submitted 2024/11/13 Platform GPL24676
Summary
To determine the transcriptomic changes of small-molecule-induced activation of ERBB4 in heart failure, we tested the effects of the two small molecules (NRG1 and EF-1) of ERBB4 agonists on the HCF (human cardiac fibroblasts) model. The transcriptional profiles of mRNA in these samples will be measured with high throughput technology. Changes in transcriptional profiles between the activation of EF-1 and NRG1 will be compared.
Published in
Small-molecule-induced ERBB4 activation to treat heart failure
Cools JMT, Goovaerts BK, Feyen E et al. · Nature communications 2025 · PMID 39794341 · doi:10.1038/s41467-024-54908-5
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Also filed as BioProject PRJNA1085772 and SRA study SRP494209. Searching any of these in the dataset finder brings you back here.

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