Gene expression analysis of nasal mucosa in birch pollen allergic and non-allergic individuals upon nasal provocation with birch pollen
RNA-seq (gene expression) · human · 46 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 46 samples: 23 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Transcriptomic Profiles of the Nasal Mucosa Following Birch Pollen Provocation Differ Between Birch Pollen-Allergic and Non-Allergic IndividualsAllergy · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE261239_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1086145 and SRA study SRP494337. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 46 samples.
How we read this: 23 replicated groups read from 46 sample titles; they account for 46 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8138434 TEB-001;N1 TEB-001;N
- GSM8138435 TEB-001;N2 TEB-001;N
- GSM8138436 TEB-002;N1 TEB-002;N
- GSM8138437 TEB-002;N2 TEB-002;N
- GSM8138438 TEB-003;N1 TEB-003;N
- GSM8138439 TEB-003;N2 TEB-003;N
- GSM8138440 TEB-004;N1 TEB-004;N
- GSM8138441 TEB-004;N2 TEB-004;N
- GSM8138442 TEB-007;N1 TEB-007;N
- GSM8138443 TEB-007;N2 TEB-007;N
- GSM8138444 TEB-008;N1 TEB-008;N
- GSM8138445 TEB-008;N2 TEB-008;N
- GSM8138446 TEB-009;N1 TEB-009;N
- GSM8138447 TEB-009;N2 TEB-009;N
- GSM8138448 TEB-010;N1 TEB-010;N
- GSM8138449 TEB-010;N2 TEB-010;N
- GSM8138450 TEB-011;N1 TEB-011;N
- GSM8138451 TEB-011;N2 TEB-011;N
- GSM8138452 TEB-012;N1 TEB-012;N
- GSM8138453 TEB-012;N2 TEB-012;N
- GSM8138454 TEB-013;N1 TEB-013;N
- GSM8138455 TEB-013;N2 TEB-013;N
- GSM8138456 TEB-014;N1 TEB-014;N
- GSM8138457 TEB-014;N2 TEB-014;N
- GSM8138458 TEB-015;N1 TEB-015;N
- GSM8138459 TEB-015;N2 TEB-015;N
- GSM8138460 TEB-017;N1 TEB-017;N
- GSM8138461 TEB-017;N2 TEB-017;N
- GSM8138462 TEB-018;N1 TEB-018;N
- GSM8138463 TEB-018;N2 TEB-018;N
- GSM8138464 TEB-022;N1 TEB-022;N
- GSM8138465 TEB-022;N2 TEB-022;N
- GSM8138466 TEB-023;N1 TEB-023;N
- GSM8138467 TEB-023;N2 TEB-023;N
- GSM8138468 TEB-024;N1 TEB-024;N
- GSM8138469 TEB-024;N2 TEB-024;N
- GSM8138470 TEB-025;N1 TEB-025;N
- GSM8138471 TEB-025;N2 TEB-025;N
- GSM8138472 TEB-026;N1 TEB-026;N
- GSM8138473 TEB-026;N2 TEB-026;N
+ 6 more — browse all 46 samples with per-sample file links →
- GSE275114 Therapy of allergic rhinitis using ribavirin spray to clear nasal commensal viruses 70 samples shares allergic, nasal
- GSE193816 A model of human asthma exacerbation identifies novel transcriptional programs and pathogenic cell circuits in the lower airway mucosa specific to allergic asthma 21 samples shares allergic, mucosa
- GSE297584 Distinct phenotypes and repertoires of bronchoalveolar and airway mucosal T cells in health and allergic asthma 11 samples shares allergic, mucosa
- GSE261706 Homo Sapiens Nasal Inferior Turbinates of house dust mite-induced allergic rhinitis and controls 8 samples shares allergic, nasal
- GSE327665 Ustekinumab Resistance in Individuals with Ulcerative Colitis is Associated with an Alteration of a Subset of Pro-inflammatory Mucosal Regulatory T cells 6 samples shares individuals, mucosa
- GSE271520 Obese individuals exhibit distinct temporal gene expression dynamics in response to influenza vaccination 489 samples shares individuals
- GSE274680 Inflammation and lymphocyte activation during longitudinal progression to rheumatoid arthritis in at-risk individuals 243 samples shares individuals
- GSE303756 Loss of tolerance in cow milk allergic endotypes is linked to allergen-specific CD4+ T cell subset outgrowth and microbial dysbioses 114 samples shares allergic
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.