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Homo Sapiens Nasal Inferior Turbinates of house dust mite-induced allergic rhinitis and controls

GSE261706 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2024/05/30 Platform GPL18573
Summary
To elucidate the epithelial cell diversity within the nasal inferior turbinates, a comprehensive investigation was conducted comparing control subjects to individuals with house dust mite-induced allergic rhinitis. This study aimed to delineate the differential expression profiles and phenotypic variations of epithelial cells in response to allergic rhinitis. This research elucidated distinct subpopulations and rare cell types of epithelial cells within the nasal turbinates, discerning alterations induced by allergic rhinitis. Furthermore, by interrogating transcriptomic signatures, the investigation provided novel insights into the cellular dynamics and immune responses underlying allergic rhinitis pathogenesis
Published in
Rare presence and function of neuroendocrine cells in the nasal mucosa
Wils T, Backaert W, Jacobs I et al. · Frontiers in immunology 2024 · PMID 39176088 · doi:10.3389/fimmu.2024.1394539
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Also filed as BioProject PRJNA1088458 and SRA study SRP495475. Searching any of these in the dataset finder brings you back here.

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