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A humanized therapeutic monoclonal anti-ASC antibody alleviates oxygen-induced retinopathy in mice

GSE261490 Mus musculus Expression profiling by high throughput sequencing 12 samples 2025/05/01 GPL24247
Summary
This study was to test the efficacy of a humanized monoclonal antibody, IC100 for ASC, an apoptosis-associated speck-like protein containing a caspase recruitment domain that is pivotal in inflammasome assembly, in the prevention and treatment of an oxygen-induced retinopathy (OIR) mouse model.
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