GEO series
B cells in triple positive antiphospholipid syndrome
GSE262240
Homo sapiens
Expression profiling by high throughput sequencing; Other
42 samples
2024/10/08
GPL24676
Summary
Peripheral B cell selection of autoreactive B cells is crucial for preventing autoimmunity. In this study, we identify that a significant proportion of antiphospholipid (aPL) B cells present in the naive compartment, exhibit polyreactivity and belong to the natural repertoire. We used scRNA Seq to follow B cells with aPL features throughout their development from naïve B cells to plasma cells in patients with PAPS.
Download
NCBI GEO page ↗
Paper (PMID 39548093) ↗
{# Names what the click gives you. "Open in finder" meant nothing to a
visitor who arrived from a search engine and has never seen the tool. #}
Find more
human RNA-seq datasets →
Similar datasets
- GSE296419 The critical role of the host endogenous immune compartment after intracerebroventricular CAR T cell therapy in recurrent GBM 143 samples
- GSE335494 B-cell depletion improves therapeutic index of combination checkpoint blockade in patients with advanced melanoma 44 samples
- GSE332623 Immunological Differences in Atopic Dermatitis Across Age Groups: Insights from Single-Cell Multi-Omics 54 samples
- GSE320042 High-resolution and noninvasive profiling of the tumor microenvironment with spatial ecotypes 38 samples
- GSE325670 Promoter mutagenesis and a massively parallel reporter screen of the MAPT locus identifies cis-regulatory elements and genetic variation effects 140 samples
- GSE317520 Mitochondrial DNA Mutations Drive Tumor Heterogeneity in Papillary Thyroid Carcinoma 92 samples
- GSE319236 Spatially resolved maternal and fetal cell contributions to severe Preeclampsia 152 samples
- GSE301785 The molecular basis for fate determination of nuclear polyadenylated RNA 131 samples
Share this dataset
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.