Chemically induced expansion of type 2 alveolar epithelial cell promotes regenerative lower airway repair
Single-cell RNA-seq · mouse · 11 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart. Read from the summary: GEO's own type field only says 'expression profiling by sequencing', so confirm it in the paper.
- Organism
- Mus musculus (mouse)
- Samples
- 11 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE262393_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1091645 and SRA study SRP497688. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 11 more — browse all 11 samples with per-sample file links →
- GSE287098 Influenza virus-induced type I interferons disrupt alveolar epithelial repair and tight junction integrity in the developing lung 96 samples shares epithelial, alveolar, induced
- GSE271272 Fibroblast-derived osteoglycin promotes alveolar epithelial cell repair 32 samples shares epithelial, alveolar, promotes
- GSE264369 Fatty acid oxidation downregulation in alveolar epithelial 2 cells promotes acute lung injury in obesity 18 samples shares epithelial, alveolar, promotes
- GSE327565 Sustained Yap/Taz activation promotes aberrant alveolar epithelial cell differentiation and drives persistent fibrotic remodeling 14 samples shares epithelial, alveolar, promotes
- GSE319684 Timecourse of FACS sorted Ly6C+ monocytes, tissue resident alveolar macrophages (trAMs), monocyte derived alveolar macrophages (bmAMs) and epithelial cells from SARS-CoV-2 (maVie16) vs. IAV (PR8) infected mouse lungs 176 samples shares epithelial, alveolar
- GSE271971 Pulmonary microvascular endothelial cells support alveolar epithelial growth via bone morphogenetic protein 6 secretion 72 samples shares epithelial, alveolar
- GSE289371 Chemically-induced protein degradation reveals inflammation-dependent requirement for Treg lineage-defining transcription factor FOXP3 58 samples shares chemically, induced
- GSE240708 Degenerative and regenerative peripheral processes are associated with persistent painful chemotherapy-induced neuropathies in males and females 53 samples shares regenerative, induced
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.