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Mitochondria–lysosome crosstalk dictates the progressive differentiation of Treg cells to limit inflammation-associated immunopathology [scRNA-seq1]

GSE262494 Mus musculus Expression profiling by high throughput sequencing; Other 8 samples Submitted 2025/11/13 Platform GPL24247
Summary
Gene expression profiling in Treg cells and non-Treg immune cells under steady-state and inflammation conditions.
Published in
Mitochondrial and lysosomal signaling orchestrates heterogeneous metabolic states of regulatory T cells
Saravia J, Chapman NM, Sun Y et al. · Science immunology 2025 · PMID 41134876 · doi:10.1126/sciimmunol.ads9456
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Direct links to NCBI, no account and no request form: the whole study as GSE262494_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1092048 and SRA study SRP497903. Searching any of these in the dataset finder brings you back here.

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