Expression data of young and aged mice derived CD8+ T cells stimulated in TCR or TRM condition for 3 days
RNA-seq (gene expression) · mouse · 3 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 3 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Age-related decline in CD8(+) tissue resident memory T cells compromises antitumor immunityNature aging · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE262773_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1093169 and SRA study SRP498535. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 3 more — browse all 3 samples with per-sample file links →
- GSE306058 scCRISPR screens of CD8⁺ T cells in young vs. aged tumors and tdLNs 11 samples shares cd8, young, aged
- GSE310273 ATAC-seq after CRISPR perturbation of CD8⁺ T cells in young vs. aged tumors 48 samples shares cd8, young, aged
- GSE304763 A pan-immunotherapy signature to predict intratumoral CD8+ T cell expansions [scTCR_immunotherapies] 91 samples shares cd8, tcr
- GSE262842 Antitumor progenitor exhausted CD8 T cells are sustained with TCR engagement [ATACseq] 24 samples shares cd8, tcr
- GSE266454 AGED CD8+ T CELLS DRIVE COGNITIVE DECLINE VIA GZMK 21 samples shares cd8, aged
- GSE275982 Clonally expanded targetable natural killer-like T cells seed the aged spinal cord to disrupt wound healing [scGEX and TCR] 24 samples shares tcr, aged
- GSE285414 Functional memory T cells are derived from exhausted clones and expanded by checkpoint blockade [scRNATCR_rechallenge] 21 samples shares tcr, derived
- GSE189297 RNA sequencing of wild type or calcineurin-deficient mouse bone marrow-derived dendritic cells stimulated with or without lipoarabinomannan (LAM) from Mycobacterium tuberculosis Aoyama-B 10 samples shares stimulated, derived
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.