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Ascorbic acid increases CD8+ T cells by binding Myh9 protein and enriching gut microbiota Akkermansia muciniphila, improves cognitive levels in middle-aged mice [RNA-seq]

GSE262962 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2025/12/04 Platform GPL23479
Summary
We implemented transcriptomic analyses of hippocampus of 8-9M mice.
Published in
Ascorbic acid attenuates immunosenescence and cognitive decline via MYH9-Mediated CD8⁺ T cell differentiation
Mi T, Yang S, Wang N et al. · Immunity & ageing : I & A 2025 · PMID 41194177 · doi:10.1186/s12979-025-00538-4
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Direct links to NCBI, no account and no request form: the whole study as GSE262962_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1095002 and SRA study SRP499071. Searching any of these in the dataset finder brings you back here.

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