Akkermansia muciniphila contributes to fasting-mediated radioprotection by inducing epigenetic and transcriptional changes in small intestinal epithelial cells
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 32 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 32 samples: 32 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Fasting primes small intestinal regeneration after damage via a microbiome-metabolite-chromatin axisProceedings of the National Academy of Sciences of the United States of America · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE306673_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1311610 and SRA study SRP613718. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 32 sample titles: 32 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9205761 1_Fed_0h
- GSM9205762 2_Fed_0h
- GSM9205763 3_Fed_0h
- GSM9205764 4_Fed_0h
- GSM9205765 1_Fed_24hpi
- GSM9205766 2_Fed_24hpi
- GSM9205767 3_Fed_24hpi
- GSM9205768 4_Fed_24hpi
- GSM9205769 1_Fed_48hpi
- GSM9205770 2_Fed_48hpi
- GSM9205771 3_Fed_48hpi
- GSM9205772 4_Fed_48hpi
- GSM9205773 1_Fed_72hpi
- GSM9205774 2_Fed_72hpi
- GSM9205775 3_Fed_72hpi
- GSM9205776 4_Fed_72hpi
- GSM9205777 1_Fast_0h
- GSM9205778 2_Fast_0h
- GSM9205779 3_Fast_0h
- GSM9205780 4_Fast_0h
- GSM9205781 1_Fast_24hpi
- GSM9205782 2_Fast_24hpi
- GSM9205783 3_Fast_24hpi
- GSM9205784 4_Fast_24hpi
- GSM9205785 1_Fast_48hpi
- GSM9205786 2_Fast_48hpi
- GSM9205787 3_Fast_48hpi
- GSM9205788 4_Fast_48hpi
- GSM9205789 1_Fast_72hpi
- GSM9205790 2_Fast_72hpi
- GSM9205791 3_Fast_72hpi
- GSM9205792 4_Fast_72hpi
- GSE242470 Intestinal Akkermansia muciniphila complements the efficacy of PD1 therapy in MAFLD-related hepatocellular carcinoma 16 samples shares akkermansia, muciniphila, intestinal
- GSE242467 Intestinal Akkermansia muciniphila complements the therapeutic efficacy of PD1 therapy by reshaping the immunosuppressive microenvironment in nonalcoholic fatty liver disease (NAFLD)-induced hepatocellular carcinoma [bulk RNA-Seq] 4 samples shares akkermansia, muciniphila, intestinal
- GSE242469 Intestinal Akkermansia muciniphila complements the therapeutic efficacy of PD1 therapy by reshaping the immunosuppressive microenvironment in nonalcoholic fatty liver disease (NAFLD)-induced hepatocellular carcinoma [scRNA-Seq] 2 samples shares akkermansia, muciniphila, intestinal
- GSE276172 RNA sequencing analysis of doxorubicin-treated mice after administration with Akkermansia muciniphila 9 samples shares akkermansia, muciniphila
- GSE254234 Akkermansia muciniphila reduces lipid absorption through activating AMPK in the jejunum 6 samples shares akkermansia, muciniphila
- GSE327232 Transcriptomic profiling of splenic CD4+ T cells in DSS-induced colitis mice treated with Akkermansia muciniphila 6 samples shares akkermansia, muciniphila
- GSE262962 Ascorbic acid increases CD8+ T cells by binding Myh9 protein and enriching gut microbiota Akkermansia muciniphila, improves cognitive levels in middle-aged mice [RNA-seq] 4 samples shares akkermansia, muciniphila
- GSE262964 Ascorbic acid increases CD8+ T cells by binding Myh9 protein and enriching gut microbiota Akkermansia muciniphila, improves cognitive levels in middle-aged mice [scRNA-seq] 3 samples shares akkermansia, muciniphila
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.