Investigation of CD64+ macrophages in bleomycin treated lungs [NGS2117]
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples: 24 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE262965_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1095007 and SRA study SRP499073. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 24 sample titles: 24 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8182211 Bleomycin_D14_Alveolar_0231 [NGS2117]
- GSM8182212 Bleomycin_D14_Alveolar_0232 [NGS2117]
- GSM8182213 Bleomycin_D14_Alveolar_0233 [NGS2117]
- GSM8182214 Bleomycin_D14_CD64_0237 [NGS2117]
- GSM8182215 Bleomycin_D14_CD64_0238 [NGS2117]
- GSM8182216 Bleomycin_D14_CD64_0239 [NGS2117]
- GSM8182217 Bleomycin_D5_Alveolar_0219 [NGS2117]
- GSM8182218 Bleomycin_D5_Alveolar_0220 [NGS2117]
- GSM8182219 Bleomycin_D5_Alveolar_0221 [NGS2117]
- GSM8182220 Bleomycin_D5_CD64_0225 [NGS2117]
- GSM8182221 Bleomycin_D5_CD64_0226 [NGS2117]
- GSM8182222 Bleomycin_D5_CD64_0227 [NGS2117]
- GSM8182223 Saline_D14_Alveolar_0228 [NGS2117]
- GSM8182224 Saline_D14_Alveolar_0229 [NGS2117]
- GSM8182225 Saline_D14_Alveolar_0230 [NGS2117]
- GSM8182226 Saline_D14_CD64_0234 [NGS2117]
- GSM8182227 Saline_D14_CD64_0235 [NGS2117]
- GSM8182228 Saline_D14_CD64_0236 [NGS2117]
- GSM8182229 Saline_D5_Alveolar_0216 [NGS2117]
- GSM8182230 Saline_D5_Alveolar_0217 [NGS2117]
- GSM8182231 Saline_D5_Alveolar_0218 [NGS2117]
- GSM8182232 Saline_D5_CD64_0222 [NGS2117]
- GSM8182233 Saline_D5_CD64_0223 [NGS2117]
- GSM8182234 Saline_D5_CD64_0224 [NGS2117]
- GSE263892 Single-cell analysis reveals Mycobacterium tuberculosis ESX-1-mediated accumulation of permissive macrophages in infected mouse lungs 6078 samples shares macrophages, lungs
- GSE319684 Timecourse of FACS sorted Ly6C+ monocytes, tissue resident alveolar macrophages (trAMs), monocyte derived alveolar macrophages (bmAMs) and epithelial cells from SARS-CoV-2 (maVie16) vs. IAV (PR8) infected mouse lungs 176 samples shares macrophages, lungs
- GSE313869 Impact of Fc engineering on the transcriptional profile of monocytes and interstitial macrophages in the lungs of Hu-FcgR Tg mice after MA30 infection 36 samples shares macrophages, lungs
- GSE201128 The response to lipopolysaccharide (LPS) of bone marrow derived macrophages treated with oxysterol binding protein (OSBP) inhibitors 30 samples shares macrophages, treated
- GSE21764 To determine the global gene expression response in murine LPS-induced macrophages treated with a bromodomain inhibitor. 24 samples shares macrophages, treated
- GSE272755 Transcriptional effects of lysosome stress on mouse bone marrow-derived macrophages and primary microglia 263 samples shares macrophages
- GSE300757 Efferocytosis induces proangiogenic function and chromatin remodeling in tumor-associated macrophages 127 samples shares macrophages
- GSE319035 P21+TREM2+-Senescent Macrophages Fuel Inflammaging and Metabolic Dysfunction-Associated Steatotic Liver Disease [NAFLD_time_course] 77 samples shares macrophages
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.