Naïve CD8 T cell RNA sequencing in C57BL/6 and MD4 mice
RNA-seq (gene expression) · mouse · 10 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 10 samples: 5 × B6_naïve CD8 T cells vs 5 × MD4_naïve CD8 T cellsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- B cells shape naive CD8+ T cell programmingThe Journal of clinical investigation · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE263132_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1095917 and SRA study SRP499597. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 2 replicated groups read from 10 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8186507 B6_naïve CD8 T cells_1 B6_naïve CD8 T cells
- GSM8186508 B6_naïve CD8 T cells_2 B6_naïve CD8 T cells
- GSM8186509 B6_naïve CD8 T cells_3 B6_naïve CD8 T cells
- GSM8186510 B6_naïve CD8 T cells_4 B6_naïve CD8 T cells
- GSM8186511 B6_naïve CD8 T cells_5 B6_naïve CD8 T cells
- GSM8186512 MD4_naïve CD8 T cells_1 MD4_naïve CD8 T cells
- GSM8186513 MD4_naïve CD8 T cells_2 MD4_naïve CD8 T cells
- GSM8186514 MD4_naïve CD8 T cells_3 MD4_naïve CD8 T cells
- GSM8186515 MD4_naïve CD8 T cells_4 MD4_naïve CD8 T cells
- GSM8186516 MD4_naïve CD8 T cells_5 MD4_naïve CD8 T cells
- GSE293533 Bulk RNA sequencing of bone marrow CD8+ T cells in BMF mice treated with or without baricitinib at different time points 16 samples shares cd8
- GSE274825 RNA sequencing of MC38 tumor cells from control-diet- and high-fat-diet-fed C57BL/6J mice 10 samples shares c57bl
- GSE316313 Single-cell RNA sequencing of MC38 subcutaneous allograft tumors in C57BL/6J mice treated with FOLFOX alone or in combination with a composite probiotics 9 samples shares c57bl
- GSE228455 Gene expression profile at single cell level of monocytes sorted from C57BL/6J mouse ear tissue at 3 weeks post Leishmania major infection [scRNA-seq] 218 samples shares c57bl
- GSE302019 Bulk RNA sequencing to investigate transcriptional profiles of lung macrophage subpopulations isolated from wild-type C57BL/6J and Spp1-EGFP knock-in reporter mice subjected to intratracheal administration of bleomycin or PBS. 24 samples shares c57bl
- GSE296763 Mitochondrial respiration is necessary for CD8 T cell proliferation and cell fate 99 samples shares cd8
- GSE279918 Gene expression profile at single cell level of lungs of adult male and female C57BL/6 mice with andwithout high-fat diet-induced obesity 12 samples shares c57bl
- GSE334845 Discovery of Tcf7 regulators with clonally-resolved CRISPR screens identifies Trim28 as a mediator of CD8 T cell differentiation in tumors [RNA-Seq] 86 samples shares cd8
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.