GEO series
Effect of whole-body deletion of Gclc on the liver
GSE263190
Mus musculus
Expression profiling by high throughput sequencing
32 samples
2024/05/29
GPL21103
Summary
The rate-limiting step in glutathione (GSH) synthesis is controlled by glutamate-cysteine ligase catalytic subunit. To investigate the impact of GSH in vivo, we induced a deletion of Gclc using a Gclcf/f Rosa26-CreERT2 mouse model and harvested liver tissue for analysis.
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Paper (PMID 39034312) ↗
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