Vg1+ gd T cells promote DC activation and CD8 T cell expansion via IL-4
RNA-seq (gene expression) · mouse · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples: 5 × IL4 vs 4 × Media vs 4 × CD40 and IL4 vs 3 × CD40Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE263267_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1096369 and SRA study SRP499850. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 4 replicated groups read from 16 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8188869 Media replicate 1 Media
- GSM8188870 Media replicate 2 Media
- GSM8188871 Media replicate 3 Media
- GSM8188872 Media replicate 4 Media
- GSM8188873 IL4 replicate 1 IL4
- GSM8188874 IL4 replicate 2 IL4
- GSM8188875 IL4 replicate 3 IL4
- GSM8188876 IL4 replicate 4 IL4
- GSM8188877 IL4 replicate 5 IL4
- GSM8188878 CD40 replicate 1 CD40
- GSM8188879 CD40 replicate 2 CD40
- GSM8188880 CD40 replicate 3 CD40
- GSM8188881 CD40 and IL4 replicate 1 CD40 and IL4
- GSM8188882 CD40 and IL4 replicate 2 CD40 and IL4
- GSM8188883 CD40 and IL4 replicate 3 CD40 and IL4
- GSM8188884 CD40 and IL4 replicate 4 CD40 and IL4
- GSE342096 Distinct activation programs in naïve and memory CD8 T cells govern progeny stemness and effector persistence 37 samples shares cd8, activation
- GSE304763 A pan-immunotherapy signature to predict intratumoral CD8+ T cell expansions [scTCR_immunotherapies] 91 samples shares cd8, expansion
- GSE270717 The m6A demethylase FTO controls activation-induced cell death in effector CD8+ T cells by modulating Fas expression 10 samples shares cd8, activation
- GSE270050 Expansion of Tumor-Infiltrating CD8+ T Cell Clonotypes Occurs in the Spleen in Response to Immune Checkpoint Blockade 29 samples shares cd8, expansion
- GSE310452 Sustained A2AR expression and loss paradoxically promote CD8+ T cell exhaustion 12 samples shares cd8, promote
- GSE327565 Sustained Yap/Taz activation promotes aberrant alveolar epithelial cell differentiation and drives persistent fibrotic remodeling 14 samples shares activation, promote
- GSE263688 Ageing promotes metastasis via activation of the integrated stress response 16 samples shares activation, promote
- GSE305975 Basal level of ATF4 promotes T cell readiness for activation-induced proliferation 29 samples shares activation, promote
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.