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Proximal tubule cell maturation rate and function are controlled by PPARα signaling in kidney organoids.

GSE263556 Homo sapiens Expression profiling by high throughput sequencing 7 samples Submitted 2024/10/11 Platform GPL24676
Summary
Kidney organoids derived from human iPSCs have cell heterogeneity of maturation. We used single-cell RNA sequencing (scRNAs-seq) to extract the factor related to proximal tubule maturation. Using the kidney organoids cultured with the factors that accelerate the maturation speed of proximal tubules extracted by the aforementioned method, we examined whether the maturity of the proximal tubules increases within the same induction period.
Published in
Proximal tubule cell maturation rate and function are controlled by PPARα signaling in kidney organoids
Sahara Y, Fukui C, Kuniyoshi Y et al. · Communications biology 2024 · PMID 39604738 · doi:10.1038/s42003-024-07069-6
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Also filed as BioProject PRJNA1098050 and SRA study SRP500568. Searching any of these in the dataset finder brings you back here.

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