GEO series
Altered TE-derived genes leads to pathogenesis of FXD [ShortReadRNASeq]
GSE264090
Homo sapiens
Expression profiling by high throughput sequencing
63 samples
2024/10/30
GPL30173
Summary
We identified known and unknown transposon elements in the cells from healthy donors, FXD patients, and ALL patients by long-read RNA-sequencing. Using these identified TEs, we analyzed the expression of TE-derived genes by shot-read (illumina) RNA-sequencing. We found that expression of some specific TE-derived genes were changed in FXD compared to those in healthy donors. These findings suggested the involvement of modified expressions of TE-derived genes in the pathogenesis of FXD.
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Paper (PMID 39465205) ↗
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