MECHANISMS UNDERLYING THE DIRECT PROGRAMMING OF MOUSE EMBRYONIC FIBROBLASTS TO THYMIC EPITHELIAL CELLS BY FOXN1 [RNA-seq]
RNA-seq (gene expression) · mouse · 13 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 13 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Mechanisms underlying the direct programming of mouse embryonic fibroblasts to thymic epithelial cells by FOXN1Development (Cambridge, England) · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE264265_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1101559 and SRA study SRP502456. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 13 more — browse all 13 samples with per-sample file links →
- GSE249753 Age-related epithelial defects limit thymic function and regeneration [single cell; Foxn1Lin] 3 samples shares thymic, foxn1, epithelial
- GSE205410 Multiple subpopulations in medullary thymic epithelial cells are regulated by Aire with distinctive modes of gene regulations [bulkRNA-seq] 47 samples shares thymic, epithelial
- GSE220665 The Transcriptional Cofactor SKI Regulates Medullary Thymic Epithelial Cell Differentiation and Peripheral T Cell Responses 42 samples shares thymic, epithelial
- GSE305453 Perturb-seq uncovers pathological obstacles to direct cardiac reprogramming in vivo 15 samples shares direct, programming
- GSE240698 Thymic epithelial organoids mediate T cell development 11 samples shares thymic, epithelial
- GSE267452 Loss of Nuclear Receptor Nr4a3 Alleviates Cellular Senescence to Promote Adult Direct Cardiac Reprogramming 54 samples shares direct, programming
- GSE240020 Age-related epithelial defects limit thymic function and regeneration 51 samples shares thymic, epithelial
- GSE267447 Loss of Nuclear Receptor Nr4a3 Alleviates Cellular Senescence to Promote Adult Direct Cardiac Reprogramming (ATAC-Seq) 16 samples shares direct, programming
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.