Disruption of the Circadian Rhythm Is Exacerbated by Aging and Partially Restored by Time-restricted Feeding
RNA-seq (gene expression) · mouse · 78 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 78 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE264350_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1102012 and SRA study SRP502671. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 78 more — browse all 78 samples with per-sample file links →
- GSE278523 Systems biology mapping of rBCG-LTAK63-induced protection against tuberculosis reveals the significance of autophagy and circadian rhythm regulation by cAMP 126 samples shares circadian, rhythm
- GSE262410 Model integration of circadian and sleep-wake driven contributions to rhythmic gene expression reveals novel regulatory principles 124 samples shares circadian, rhythm
- GSE236201 Maternal Circadian Rhythms during Pregnancy Dictate Metabolic Plasticity in Offspring 96 samples shares circadian, rhythm
- GSE262714 The Core Circadian Clock Factor, Bmal1, Transduces Sex-specific Differences in Both Rhythmic and Nonrhythmic Gene Expression in the Mouse Heart 96 samples shares circadian, rhythm
- GSE301278 Circadian Rhythm in Coronavirus Pneumonia Severity 91 samples shares circadian, rhythm
- GSE308220 Circadian rhythms in microglia mediate early life synaptic development in a sex-specific manner. 75 samples shares circadian, rhythm
- GSE288747 The liver clock drives circadian rhythms in white adipose tissue [WTKOLRE] 72 samples shares circadian, rhythm
- GSE267751 Time-restricted feeding prevents memory impairments induced by obesogenic diet consumption in mice, in part through hippocampal thyroid hormone signaling. 71 samples shares time-restricted, feeding
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.