PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer [Normal Chow diet]
RNA-seq (gene expression) · mouse · 14 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 14 samples: 14 × Normal Chow DietGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancerCell metabolism · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE264520_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1102893 and SRA study SRP503170. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 14 samples.
How we read this: 1 replicated groups read from 14 sample titles; they account for 14 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8219433 Normal Chow Diet 1 Normal Chow Diet
- GSM8219434 Normal Chow Diet 2 Normal Chow Diet
- GSM8219435 Normal Chow Diet 3 Normal Chow Diet
- GSM8219436 Normal Chow Diet 4 Normal Chow Diet
- GSM8219437 Normal Chow Diet 5 Normal Chow Diet
- GSM8219438 Normal Chow Diet 6 Normal Chow Diet
- GSM8219439 Normal Chow Diet 7 Normal Chow Diet
- GSM8219440 Normal Chow Diet 8 Normal Chow Diet
- GSM8219441 Normal Chow Diet 9 Normal Chow Diet
- GSM8219442 Normal Chow Diet 10 Normal Chow Diet
- GSM8219443 Normal Chow Diet 11 Normal Chow Diet
- GSM8219444 Normal Chow Diet 12 Normal Chow Diet
- GSM8219445 Normal Chow Diet 13 Normal Chow Diet
- GSM8219446 Normal Chow Diet 14 Normal Chow Diet
- GSE264521 PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer [Western Diet + CCl4] 19 samples shares pkd1, steatohepatitis, cirrhotic, promoting, inhibit, without, mutant, clones
- GSE239861 Bardoxolone methyl improves nonalcoholic steatohepatitis through inhibition of macrophage recruitment 12 samples shares steatohepatitis, inhibit
- GSE277680 Mitochondrial Ferritin Inhibition Aggravates Pacing-induced Ventricular Arrhythmias after Myocardial Infarction by Promoting Cardiomyocytes Ferroptosis 12 samples shares promoting, inhibit
- GSE313863 GALNT3 inhibits the progression of cerebral ischemia-reperfusion injury by promoting O-glycosylation of TREM2 12 samples shares promoting, inhibit
- GSE98782 Therapeutic Inhibition of Inflammatory Monocyte Recruitment Reduces Steatohepatitis and Liver Fibrosis 8 samples shares steatohepatitis, inhibit
- GSE278570 Neutrophils physically interact with tumor cells to form a signaling niche promoting breast cancer aggressiveness 309 samples shares promoting
- GSE302682 Sleeping Beauty mutagenesis identifies BACH2 and other regulators promoting CD8+ T cell persistence and effector function under tumor-associated chronic antigen stimulation - RNAseq 66 samples shares promoting
- GSE196790 Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk promoting immunosuppression and immunotherapy resistance 54 samples shares promoting
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.