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SIRT1 involvement in the metabolism and differentiation of human stem cells.

GSE264628 Homo sapiens Expression profiling by high throughput sequencing 4 samples Submitted 2026/04/22 Platform GPL24676
Summary
SIRT1, a histone deacetylase enzyme, is implicated in cellular differentiation and metabolic regulation. However, its dynamic transcriptomic role remains elusive. Here, we investigate SIRT1's involvement using H9 human embryonic stem cells (hESCs) with complete SIRT1 deletion (H9 SIRT1 -/-) undergoing dopaminergic neuron differentiation, followed by scRNAseq analysis
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Also filed as BioProject PRJNA1103681 and SRA study SRP503531. Searching any of these in the dataset finder brings you back here.

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