Transcriptome profiles characteristics of peripheral immune in Severe Fever with Thrombocytopenia Syndrome patients
RNA-seq (gene expression) · human · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 20 samples: 6 × PBMCs, A vs 6 × PBMCs, C vs 5 × PBMCs, B vs 3 × PBMCs, DGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Transcriptome Profiles Characteristics of the Peripheral Immune in Patients with Severe Fever with Thrombocytopenia SyndromeJournal of inflammation research · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE264635_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1103697 and SRA study SRP503551. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 4 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8224308 PBMCs, A1 PBMCs, A
- GSM8224309 PBMCs, A2 PBMCs, A
- GSM8224310 PBMCs, A3 PBMCs, A
- GSM8224311 PBMCs, A4 PBMCs, A
- GSM8224312 PBMCs, A5 PBMCs, A
- GSM8224313 PBMCs, A6 PBMCs, A
- GSM8224314 PBMCs, B1 PBMCs, B
- GSM8224315 PBMCs, B2 PBMCs, B
- GSM8224316 PBMCs, B3 PBMCs, B
- GSM8224317 PBMCs, B4 PBMCs, B
- GSM8224318 PBMCs, B5 PBMCs, B
- GSM8224319 PBMCs, C1 PBMCs, C
- GSM8224320 PBMCs, C2 PBMCs, C
- GSM8224321 PBMCs, C3 PBMCs, C
- GSM8224322 PBMCs, C4 PBMCs, C
- GSM8224323 PBMCs, C5 PBMCs, C
- GSM8224324 PBMCs, C6 PBMCs, C
- GSM8224325 PBMCs, D1 PBMCs, D
- GSM8224326 PBMCs, D2 PBMCs, D
- GSM8224327 PBMCs, D3 PBMCs, D
- GSE326415 Paired Transcriptomic Profiling of Airspace and Peripheral Blood Mononuclear Cells in Severe ARDS 63 samples shares peripheral, severe
- GSE290782 Benralizumab treatment in patients with severe asthma: A comparative analysis of T-cell gene expression profiles and identification of response-associated genes 34 samples shares profiles, severe
- GSE276583 Gene expression profiles of healthy mononuclear cells and eosinophils and asthma (moderate and severe) eosinophils 17 samples shares profiles, severe
- GSE310998 Peripheral blood transcriptomics identifies cohesin–chromatin and immune dysregulation in tics and Tourette syndrome 48 samples shares peripheral
- GSE281106 Single-cell RNA-seq of peripheral blood links cell-type-specific regulation of splicing to autoimmune and inflammatory diseases [scRNAseq_KR_SGI] 352 samples shares peripheral
- GSE327707 Sorted bulk RNA-seq profiling of human peripheral blood mononuclear cell populations across diverse in vitro immune stimuli 150 samples shares peripheral
- GSE289582 Baseline tumor features and peripheral blood immune dynamics that underlie efficacy in MSS metastatic colorectal cancer treated with regorafenib, ipilimumab, and nivolumab [Blood] 115 samples shares peripheral
- GSE305811 Immune and Transcriptional Landscape of Endometrial Receptivity at P+5 Phase: A Triad Analysis of EIN, RIF, and Control Endometrial Profiles 92 samples shares profiles
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.