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Loss of CLN3 in HEK cells

GSE265831 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/12/23 Platform GPL15433
Summary
To understand the consequences of CLN3 loss, we performed RNAseq in HEK cells with CRISPR-Cas9-mediated KO of CLN3 (CLN3-KO) or parental HEK WT cells.
Published in
Loss of the lysosomal protein CLN3 triggers c-Abl-dependent YAP1 pro-apoptotic signaling
Domingues N, Calcagni' A, Freire S et al. · EMBO reports 2025 · PMID 41198904 · doi:10.1038/s44319-025-00613-3
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Also filed as BioProject PRJNA1104285 and SRA study SRP503880. Searching any of these in the dataset finder brings you back here.

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