Biological effects of recombinant S100A8, recombinant S100A9, and recombinant S100A8/S100A9 on human renal tubular epithelial cells (HK-2)
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE265848_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1104534 and SRA study SRP504024. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 12 more — browse all 12 samples with per-sample file links →
- GSE339245 RNA-seq transcriptome profiling of HK-2 human renal tubular epithelial cells upon gene knockdown mediated by sgRNA 6 samples shares hk-2, epithelial, tubular, renal
- GSE307014 Recombinant Spider Silk Membranes Promote Human Renal Epithelial Differentiation and Function 15 samples shares recombinant, epithelial, renal
- GSE326160 Secreted Protein Combination GAPDH/S100A8/S100A9 from Human Expanded Potential Stem Cells Counteracts Mesenchymal Stem Cell Senescence 3 samples shares s100a8, s100a9
- GSE269418 Effect of the sGC activator BAY 60-2770 on human proximal tubular (HK-2) cells under hypoxia and after TGF-β1 treatment 24 samples shares hk-2, tubular
- GSE294961 Design and Biological Activity of a Novel Urea Compound Against Glioblastoma [HK-217_scRNAseq_MXC-017_in_vitro] 4 samples shares hk-2, biological
- GSE294815 Design and Biological Activity of a Novel Urea Compound Against Glioblastoma [HK-244_scRNAseq_MXC-017_in_vitro] 4 samples shares hk-2, biological
- GSE270695 S100A8/A9 contributes to inflammatory exacerbations in neutrophils and monocytes from PAMI syndrome 52 samples shares s100a8
- GSE301531 S100A8/A9 Priming Alters Translational Related Proteins and Upregulates Pro‑Regenerative Factors in Mesenchymal Stromal Cells 18 samples shares s100a8
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.