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Effects of overexpression of MrgD on human pulmonary artery smooth muscle cells.

GSE265849 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/04/08 Platform GPL24676
Summary
MrgD is a new member of the RAS system and belongs to a group of G protein-coupled receptors. The main function of these receptors is to sense and generate itching or pain signals. In recent years, more and more cardiovascular research has been conducted, and it may have anti-fibrosis resistance. inflammation and other functional effects. The RAS system can maintain homeostasis in pulmonary hypertension, but the role of MrgD in pulmonary hypertension is unclear and how it affects downstream signaling pathways. Taken together, our data provide a molecular framework for the role of MrgD in pulmonary hypertension.
Published in
MrgD as a Novel Modeling and Treatment Target for Pulmonary Hypertension
Zhong H, Yao L, An H et al. · Arteriosclerosis, thrombosis, and vascular biology 2025 · PMID 40143817 · doi:10.1161/ATVBAHA.124.322337
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Also filed as BioProject PRJNA1104536 and SRA study SRP504030. Searching any of these in the dataset finder brings you back here.

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