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Gene expression prolifes at single cell levels of neural crest cells with augmented bone morphogenetic protein (BMP) signaling.

GSE265974 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2025/04/25 Platform GPL24247
Summary
Transgenic mice expressing constitutively activated BMP type 1 receptor (caAcvr1) in neural crest cells (NCCs)(P0-Cre;caAcvr1 mice, hereafter, caAcvr1 mut mice) develop ectopic cartilage in the face but not in trunk region despite both facial and trunk region composed of NCCs. This study was aimed to identify genes that expressions are changed only in cranial NCCs by BMP signaling, but not in trunk NCCs. The genes were candidate genes involved in BMP-induced ectopic cartilage formation in the face.
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Direct links to NCBI, no account and no request form: the whole study as GSE265974_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1105070 and SRA study SRP504328. Searching any of these in the dataset finder brings you back here.

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