← BioTransfer GEO Dataset Finder
GEO series

RoCK and ROI: a single-cell RNA-sequencing method with enhanced transcriptome information via targeted enrichment of transcripts and preselected, region-specific sequencing II

GSE266117 Homo sapiens; Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2024/05/07 Platform GPL24676Platform GPL25526
Summary
Many scRNAseq-based methods suffer from a high number of non-detects and a bias towards the 3' or 5' end of transcripts. We developed a method termed RoCK and ROI to address these two biases. RoCK and ROI leads to the enrichment of the transcriptome profile of cells with information on transcripts of interest
Published in
RoCK and ROI: single-cell transcriptomics with multiplexed enrichment of selected transcripts and region-specific sequencing
Moro G, Mallona I, Barz MJ et al. · Nature communications 2025 · PMID 41372142 · doi:10.1038/s41467-025-66248-z
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE266117_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1105909 and SRA study SRP504631. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 4 more — browse all 4 samples with per-sample file links →

Similar datasets

Search all RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.