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The role of macrophage VCAM-1 in atherosclerosis and inflammation

GSE266296 Mus musculus Expression profiling by high throughput sequencing 28 samples 2024/05/06 GPL17021
Summary
VCAM-1 is known to be expressed by endothelial cells. We showed that this is also expressed by atherosclerotic plaque macrophages. However, the merit of this adhesion molecule is now known in atherosclerosis. In this RNA sequencing experiment, we analyzed VCAM-1+ vs. - atherosclerotic plaque macrophages. Additionally, we sorted macrophages from atherosclerotic plaques of mice after mitochondrial biogenesis gene Cmpk2 silencing in macrophages in vivo.
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