SASP-related signals and SASP gene expression profiles in senescent cells after 18β-GA treatment.
RNA-seq (gene expression) · human · 3 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 3 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE266404_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1106921 and SRA study SRP505262. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 3 more — browse all 3 samples with per-sample file links →
- GSE335811 Macrophage-Induced Senescent Cancer-Associated Fibroblasts Promote SASP-Mediated Chemoresistance in Colorectal Cancer 12 samples shares sasp, senescent
- GSE282913 Gene Expression Analysis of CD4 T Cells in Autoimmune Pancreatitis: Treatment-Correlated Expression Profiles 45 samples shares treatment, profiles
- GSE290782 Benralizumab treatment in patients with severe asthma: A comparative analysis of T-cell gene expression profiles and identification of response-associated genes 34 samples shares treatment, profiles
- GSE206078 ZNF512B Safeguards Genome Integrity at Regulatory Regions to Repress SASP and Inflammation 37 samples shares sasp
- GSE279410 Mitochondrial metabolism and epigenetic crosstalk drive the SASP (ChIP-seq) 30 samples shares sasp
- GSE283522 The spatially informed mFISHseq assay resolves biomarker discordance and predicts treatment response in breast cancer 1254 samples shares treatment
- GSE292969 Effect of CCS1477 treatment on gene expression in NRF2-activated lung cancer cells 18 samples shares treatment
- GSE171741 Albumin treatment transcriptionally reprograms circulating immune cells in patients with acutely decompensated cirrhosis 139 samples shares treatment
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.