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Induction of ER stress in SHSY5Y human neuroblastoma cells by thapsigargin treatment

GSE266545 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/01/01 Platform GPL24676
Summary
To identify the impact of ER stress on other cellular organelles, cells were treated with ER stress inducer thapsigargin. Transcriptomic profile revealed increased ER stress levels. Deregulated genes was further screened to identify novel ER stress markers of other organelles. Functional charecterization of novel markers were performed to gain insight of the observation.
Published in
The impact of ER(UPR) on mitochondrial integrity mediated by PDK4
Mallick P, Maity S, Mondal R et al. · Cell death & disease 2025 · PMID 40730554 · doi:10.1038/s41419-025-07743-5
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Also filed as BioProject PRJNA1107564 and SRA study SRP505683. Searching any of these in the dataset finder brings you back here.

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