GEO series
Anti-Fibrotic Effects Of A Novel Long-Acting Fgf21 Analogue Zalfermin
GSE267229
Mus musculus
Expression profiling by high throughput sequencing
19 samples
2025/06/01
GPL19057
Summary
The potential clinical benefits of FGF21 analogues for the treatment of MASH has evolved significantly within the last years. However, despite clinical meaningful effect on MASH resolution and fibrosis the body weight loss in humans have been less impressive. Thus, a combination of an FGF21 analogue with a GLP-1 receptor agonist may add additional benefit to the treatment of MASH due to complimentary mode of action compared to stand alone therapies
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