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CRISPR/Cas9 regulates EphA2-CDH1 axis to inhibit the migration of castration-resistant prostate cancer cells

GSE267508 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2024/05/20 Platform GPL24676
Summary
We ued CRISPR/Cas9 to knock out EphA2 gene in PC3 cells, and overexpress EphA2 gene in Du145 cells with overexpressed plasmids to explore the underlying mechanisms of EphA2 function in castration-resistant prostate cancer(CRPC) and clinical relevance, providing more evidence for EphA2 as a potential therapeutic target for CRPC.
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Direct links to NCBI, no account and no request form: the whole study as GSE267508_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1111754 and SRA study SRP507752. Searching any of these in the dataset finder brings you back here.

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