Myeloid TET2-IL-1 axis controls sympathetic-epithelial interaction to modulate intestinal inflammation
RNA-seq (gene expression) · mouse · 11 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 11 samples: 11 × CD11b_bulkGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE267700_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1112425 and SRA study SRP508180. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 11 samples.
How we read this: 1 replicated groups read from 11 sample titles; they account for 11 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8273284 CD11b_bulk_1 CD11b_bulk
- GSM8273285 CD11b_bulk_2 CD11b_bulk
- GSM8273286 CD11b_bulk_3 CD11b_bulk
- GSM8273287 CD11b_bulk_4 CD11b_bulk
- GSM8273288 CD11b_bulk_5 CD11b_bulk
- GSM8273289 CD11b_bulk_6 CD11b_bulk
- GSM8273290 CD11b_bulk_7 CD11b_bulk
- GSM8273291 CD11b_bulk_8 CD11b_bulk
- GSM8273292 CD11b_bulk_9 CD11b_bulk
- GSM8273293 CD11b_bulk_10 CD11b_bulk
- GSM8273294 CD11b_bulk_11 CD11b_bulk
- GSE322757 IL-17RC signaling connects intestinal microbiota and neuroimmune interactions in atherosclerosis 42 samples shares interaction, intestinal
- GSE318434 Endothelial TGFβ signaling regulates choroidal neovascularization severity via myeloid–endothelial interaction 40 samples shares interaction, myeloid
- GSE269507 The interleukin 22–oncostatin M axis promotes intestinal inflammation and tumorigenesis [scRNA-seq] 12 samples shares intestinal, axis
- GSE262065 A small intestinal bile acid modulates the gut microbiome to improve host metabolic phenotypes following bariatric surgery 10 samples shares intestinal, modulate
- GSE316171 Fibroblast Growth Factor Receptor Signaling in Maturing Osteoblasts Controls Cell-Matrix Interactions Critical for Osteocyte Survival 8 samples shares interaction, controls
- GSE149674 Dynamic Foxp3-chromatin interaction controls tunable Treg cell function 94 samples shares interaction, controls
- GSE268623 Dynamic Foxp3-chromatin interaction controls tunable Treg cell function [Cut&Run Foxp3 Batf Ets1] 24 samples shares interaction, controls
- GSE255212 Transcriptomic Signatures of WNT-Driven Pathways and Granulosa Cell-Oocyte Interaction during Primordial Follicle Activation 762 samples shares interaction
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.