PPARγ-dependent Remodeling of Translational Machinery in Adipose Progenitors is Impaired in Obesity
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples: 3 × eWAT, Veh, vs 3 × eWAT, Rosi, vs 3 × input, Veh, vs 3 × input, Rosi,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- PPARγ-dependent remodeling of translational machinery in adipose progenitors is impaired in obesityCell reports · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE268058_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1114106 and SRA study SRP506987. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 24 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8262105 obob, rosi, eWAT, biological replicate 1, scRNAseq
- GSM8262106 obob, rosi, eWAT, biological replicate 2, scRNAseq
- GSM8262107 obob, rosi, iWAT, biological replicate 1, scRNAseq
- GSM8262108 obob, rosi, iWAT, biological replicate 2, scRNAseq
- GSM8262109 obob, veh, eWAT, biological replicate 1, scRNAseq
- GSM8262110 obob, veh, eWAT, biological replicate 2, scRNAseq
- GSM8262111 obob, veh, iWAT, biological replicate 1, scRNAseq
- GSM8262112 obob, veh, iWAT, biological replicate 2, scRNAseq
- GSM8262113 WT, veh, eWAT, biological replicate 1, scRNAseq
- GSM8262114 WT, veh, eWAT, biological replicate 2, scRNAseq
- GSM8262115 WT, veh, iWAT, biological replicate 1, scRNAseq
- GSM8262116 WT, veh, iWAT, biological replicate 2, scRNAseq
- GSM8285185 eWAT, Veh, biological replicate1 eWAT, Veh,
- GSM8285186 eWAT, Veh, biological replicate2 eWAT, Veh,
- GSM8285187 eWAT, Veh, biological replicate3 eWAT, Veh,
- GSM8285188 eWAT, Rosi, biological replicate1 eWAT, Rosi,
- GSM8285189 eWAT, Rosi, biological replicate2 eWAT, Rosi,
- GSM8285190 eWAT, Rosi, biological replicate3 eWAT, Rosi,
- GSM8285191 input, Veh, biological replicate1 input, Veh,
- GSM8285192 input, Veh, biological replicate2 input, Veh,
- GSM8285193 input, Veh, biological replicate3 input, Veh,
- GSM8285194 input, Rosi, biological replicate1 input, Rosi,
- GSM8285195 input, Rosi, biological replicate2 input, Rosi,
- GSM8285196 input, Rosi, biological replicate3 input, Rosi,
- GSE267192 PPARγ-dependent Remodeling of Translational Machinery in Adipose Progenitors is Impaired in Obesity [scRNA-seq] 12 samples shares ppar, translational, progenitors, remodeling, dependent, machinery, impaired, adipose
- GSE315007 Sex- and hepatocyte Pparg-dependent hepatic effects of a high fat diet containing 60% kcal from fat and 2% cholesterol, which was supplemented with 10% fructose in the drinking water (HFC+Fr) to induce diet-induced obesity in male and female mice. 30 samples shares ppar, dependent
- GSE301108 Stag2 dependent chromatin remodeling enforces the erythroid-specific Gata1 cistrome 45 samples shares remodeling, dependent
- GSE284354 Excitation-contraction coupling, cardiomyocyte electrophysiology, and transcriptome changes in two translational HFpEF murine models: Aetiology and sex-dependent differences 23 samples shares translational, dependent
- GSE283892 A subcellular map of translational machinery composition and regulation at the single-molecule level [ALIBi_Nmd3_Gnl3_KD] 17 samples shares translational, machinery
- GSE224160 Malaria pigment hemozoin-induced chromatin remodeling of mouse hematopoietic stem and progenitor cells, granulocyte-macrophage progenitors, and bone marrow monocytes 12 samples shares progenitors, remodeling
- GSE283890 A subcellular map of translational machinery composition and regulation at the single-molecule level [ALIBi_Lsg1_KD] 12 samples shares translational, machinery
- GSE261417 Robust single nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity 11 samples shares remodeling, adipose
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.