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Single-cell joint analysis of DNA oxidative damage and transcriptome [Hela RNA]

GSE268553 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/01/06 Platform GPL24676
Summary
We used a new technology, named Paired-Damage, to perform simultaneous profiling of DNA oxidative damage and transcriptome on Hela cells and mouse cortex at single-cell level. We also performed matched damagenome, ATAC-seq and RNA-seq of Hela cells at bulk level.
Published in
Single-cell parallel analysis of DNA damage and transcriptome reveals selective genome vulnerability
Bai D, Cao Z, Attada N et al. · Nature methods 2025 · PMID 40128288 · doi:10.1038/s41592-025-02632-3
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Also filed as BioProject PRJNA1117785 and SRA study SRP510444. Searching any of these in the dataset finder brings you back here.

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