MGA directly recruits SETDB1/ATF7IP for histone H3K9me3 on meiosis-related genes in mouse embryonic stem cells.
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 12 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 12 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- MGA directly recruits SETDB1/ATF7IP for histone H3K9me3 mark on meiosis-related genes in mouse embryonic stem cellsiScience · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE268907_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1119445 and SRA study SRP511357. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 12 sample titles: 12 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8302551 control1 ESCs for RNA-seq
- GSM8302552 control2 ESCs for RNA-seq
- GSM8302553 MGAdeltaFAM1 ESCs for RNA-seq
- GSM8302554 MGAdeltaFAM2 ESCs for RNA-seq
- GSM8302555 Input sample of control ESCs for ChIP-seq
- GSM8302556 H3K9me3 sample of control ESCs for ChIP-seq
- GSM8302557 Input sanmple of MGAdeltaFAM ESCs for ChIP-seq
- GSM8302558 H3K9me3 sample of MGAdeltaFAM ESCs for ChIP-seq
- GSM8850309 Input sample of control ESCs for dFN
- GSM8850310 H3K9me3 sample of control ESCs for dFN
- GSM8850311 Input sample of Atf7ipdeltaFN ESCs
- GSM8850312 H3K9me3 sample of Atf7ipdeltaFN ESCs
- GSE266098 SETDB1 suppresses interferon responses and NK cell-mediated immunosurveillance specifically in monocytic AML: H3K9me3 ChIP-seq of cSAM leukemia cells with Setdb1 depletion [ChIP-seq] 2 samples shares h3k9me3, setdb1
- GSE233396 Characterization of the role of SETDB1 in Muscle stem cells during skeletal muscle regeneration 10 samples shares setdb1
- GSE233041 The H3K9me3 heterochromatin integrity and function are sustained by H3K9me3 methyltransferases-HP1 dependencies 294 samples shares h3k9me3
- GSE309424 SETDB1/HUSH modulates Xist RNA levels during establishment of X chromosome inactivation 292 samples shares setdb1
- GSE231845 The H3K9me3 heterochromatin integrity and function are sustained by H3K9me3 methyltransferases-HP1 dependencies [ChIP-Seq] 216 samples shares h3k9me3
- GSE312320 SETDB1/HUSH modulates Xist RNA levels during establishment of X chromosome inactivation [ChIP-Seq, 2] 132 samples shares setdb1
- GSE310108 SETDB1/HUSH modulates Xist RNA levels during establishment of X chromosome inactivation [RNA-Seq] 112 samples shares setdb1
- GSE273948 Nuclear polysaccharides maintain H3K9me3-heterochromatin and genomic stability 56 samples shares h3k9me3
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.