LAIR1 prevents excess inflammatory tissue damage in S. aureus skin infection and Cutaneous T-cell Lymphoma [BMDM]
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- LAIR1 prevents excess inflammatory tissue damage in S. aureus skin infection and Cutaneous T-cell LymphomabioRxiv : the preprint server for biology · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE269178_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1120460 and SRA study SRP512039. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 12 more — browse all 12 samples with per-sample file links →
- GSE271812 Rebalancing Viral and Immune Damage versus Tissue Repair Prevents Death from Lethal Influenza Infection 49 samples shares prevents, damage
- GSE286079 Epicutaneous Staphylococcus aureus exposure triggers lung inflammation via epithelia-intrinsic IL-36R signaling in a murine model of the atopic march 25 samples shares cutaneous, aureus
- GSE272298 Transcriptional response of mouse BMDMs to diverse lysosomal stressors [HEX000414] 90 samples shares bmdm
- GSE181643 Oxygen-dependent changes and lysosome activity-dependent changes of gene expression in BMDM after LPS treatment 72 samples shares bmdm
- GSE272357 Transcriptional response of BMDMs to CRISPR KO of key lysosomal genes [HEX000527] 69 samples shares bmdm
- GSE279654 BMDM from Young and Aged Mice Treated with β-glucan 42 samples shares bmdm
- GSE181641 Oxygen-dependent changes of gene expression in BMDM after LPS treatment 36 samples shares bmdm
- GSE181642 Lysosome activity-dependent changes of gene expression in BMDM after LPS treatment 36 samples shares bmdm
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.