Mechanistic basis of gene regulation by SRCAP and H2A.Z (Mnase-Seq)
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 12 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × MN high NT vs 3 × MN high IAA vs 3 × MN low NT vs 3 × MN low IAAGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Mechanisms of gene regulation by SRCAP and H2A.ZNature communications · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE269307_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1120932 and SRA study SRP512309. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8312753 MN high NT 1 MN high NT
- GSM8312754 MN high IAA 1 MN high IAA
- GSM8312755 MN low NT 1 MN low NT
- GSM8312756 MN low IAA 1 MN low IAA
- GSM8312757 MN high NT 2 MN high NT
- GSM8312758 MN high IAA 2 MN high IAA
- GSM8312759 MN low NT 2 MN low NT
- GSM8312760 MN low IAA 2 MN low IAA
- GSM8312761 MN high NT 3 MN high NT
- GSM8312762 MN high IAA 3 MN high IAA
- GSM8312763 MN low NT 3 MN low NT
- GSM8312764 MN low IAA 3 MN low IAA
- GSE269304 Mechanistic basis of gene regulation by SRCAP and H2A.Z (ChIP-Seq) 102 samples shares srcap, h2a, mechanistic, basis
- GSE269302 Mechanistic basis of gene regulation by SRCAP and H2A.Z (ATAC-Seq) 34 samples shares srcap, h2a, mechanistic, basis
- GSE287553 Mechanistic basis of gene regulation by SRCAP and H2A.Z (CUT&RUN) 2 samples shares srcap, h2a, mechanistic, basis
- GSE269305 Mechanistic basis of gene regulation by SRCAP and H2A.Z (CUT&Tag) 2 samples shares srcap, h2a, mechanistic, basis
- GSE269309 Mechanistic basis of gene regulation by SRCAP and H2A.Z (RNA-Seq) 30 samples shares srcap, h2a, mechanistic, basis
- GSE269310 Mechanisms of gene regulation by SRCAP and H2A.Z 186 samples shares srcap, h2a
- GSE299108 R-loops shape the H2A.Z landscape and promote balanced lineage allocation during differentiation [MNase-Seq] 12 samples shares h2a, mnase-seq
- GSE294945 Mechanistic basis for protection against fatty liver disease by CIDEB loss-of-function mutations 20 samples shares mechanistic, basis
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.