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RCOR2 downregulates RNF43 via LSD1-mediated histone demethylation in cancer cells

GSE269916 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 8 samples Submitted 2025/06/28 Platform GPL18573
Summary
RCOR2 and LSD1 directly co-binds to RNF43 gene. RCOR2 knockout does not affect LSD1 binding on RNF43 gene.
Published in
Tumoral RCOR2 promotes tumor development through dual epigenetic regulation of tumor plasticity and immunogenicity
Bao L, Zhu M, Luo M et al. · The Journal of clinical investigation 2025 · PMID 40608411 · doi:10.1172/JCI188801
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Also filed as BioProject PRJNA1124114 and SRA study SRP514017. Searching any of these in the dataset finder brings you back here.

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