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RCOR2 downregulates CIITA via HDAC1-mediated histone deacetylation in cancer cells [ChIP-seq]

GSE270024 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 12 samples 2025/06/28 GPL18573
Summary
RCOR2 and HDAC1 directly co-binds to CIITA gene. RCOR2 knockout does not affect HDAC1 binding on CIITA gene. RCOR2 has no binding on most MHCII genes.
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