Cell-of-origin epigenome underlies SS18::SSX-mediated transformation [RNA-seq]
RNA-seq (gene expression) · mouse · 21 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 21 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- The fibroblast epigenome underlies SS18::SSX-mediated transformation in synovial sarcomaNature communications · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE270370_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1126264 and SRA study SRP515128. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 21 more — browse all 21 samples with per-sample file links →
- GSE270369 Cell-of-origin epigenome underlies SS18::SSX-mediated transformation [ChIP-seq] 27 samples shares ss18, cell-of-origin, transformation, ssx-mediated, epigenome, underlies
- GSE216769 The fibroblast epigenome underlies SS18::SSX-mediated transformation in synovial sarcoma 18 samples shares ss18, transformation, ssx-mediated, epigenome, underlies
- GSE213265 The fibroblast epigenome underlies SS18::SSX-mediated transformation in synovial sarcoma 7 samples shares ss18, transformation, ssx-mediated, epigenome, underlies
- GSE269772 SS18::SSX redistributes BAF chromatin remodelers selectively to activate and repress transcription [RNA-Seq] 46 samples shares ss18, rna-seq
- GSE266276 Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in synovial sarcoma [RNA-seq_Utah] 9 samples shares ss18, rna-seq
- GSE269773 SS18::SSX redistributes BAF chromatin remodelers selectively to activate and repress transcription [scRNA-Seq] 5 samples shares ss18, rna-seq
- GSE293599 The Polycomb Protein EED Constrains the SCLC Neuroendocrine Phenotype and Drives Lung Cancer Histological Transformation [Bulk RNA-seq] 50 samples shares transformation, rna-seq
- GSE269006 YAP1 is a key regulator of EWS::FLI1-dependent malignant transformation upon IGF-1 mediated reprogramming of bone mesenchymal stem cells [RNA-seq] 15 samples shares transformation, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.