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Molecular classification of meningioma predicts the response to surgical resection and adjuvant radiotherapy.

GSE270375 Homo sapiens (human) DNA methylation 1378 samples Submitted 2024/08/21 Platform GPL24676Platform GPL23976
At a glance

DNA methylation · human · 1378 samples

What it is
DNA methylationChemical marks on DNA that help switch genes on or off.
Organism
Homo sapiens (human)
Samples
1378 samples: 314 × Tumor methylation I vs 59 × Tumor methylation CW vs 27 × Tumor methylation NWGroups are read from the sample names, not from the paper. Check the list below.
Data you can get
A processed expression table (series matrix) and the array files, from NCBI.
SuperSeries — this record groups several sub-series.
Summary (written by the submitters)
This SuperSeries is composed of the SubSeries listed below.
This dataset
Download · which file do I need?

Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE270375_RAW.tar (it can run to tens of gigabytes).

3 · Start from the raw reads

Raw sequencing reads

The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.

What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.

Also filed as BioProject PRJNA1126283. Searching any of these in the dataset finder brings you back here.

Study design
314 × Tumor methylation I vs 59 × Tumor methylation CW vs 27 × Tumor methylation NW

Supports a between-group comparison across 400 samples.

How we read this: 3 replicated groups read from the first 400 of 1378 sample titles; they account for 400 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.

Samples in this study

+ 1338 more — browse all 1378 samples with per-sample file links →

Datasets on a similar topic

Search all human methylation datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.