Pharmacological or genetic inhibition of LTCC promotes cardiomyocyte proliferation through inhibition of calcineurin activity
RNA-seq (gene expression) · human · 10 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 10 samples: 9 distinct titles, 1 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Pharmacological or genetic inhibition of LTCC promotes cardiomyocyte proliferation through inhibition of calcineurin activityNPJ Regenerative medicine · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE270406_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1126314 and SRA study SRP515115. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 10 sample titles: 9 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8342074 DMSO_A2
- GSM8342075 DMSO_B9
- GSM8342076 DMSO_D6
- GSM8342077 DMSO_E10
- GSM8342078 DMSO_G3
- GSM8342079 Nifedipine_B4
- GSM8342080 Nifedipine_C1
- GSM8342081 Nifedipine_D7
- GSM8342082 Nifedipine_D12
- GSM8342083 Nifedipine_G9
- GSE314304 IL-11 receptor is a novel target for drug development with pharmacological activity in fibro-inflammatory disease 96 samples shares pharmacological, activity
- GSE284664 RESET: A reversible TCR-coupled antigen receptor with superior targeting sensitivity and pharmacologically controlled anti-tumor activity 62 samples shares pharmacological, activity
- GSE245739 The transcription factor IRF4 impedes human CD8 T-cell function and promotes cells proliferation and PD-1 expression 40 samples shares proliferation, promotes
- GSE272538 A novel association of EZH2 and E2F1 promotes breast cancer cell proliferation through chromatin remodeling [RNA-Seq] 18 samples shares proliferation, promotes
- GSE286315 HOXC4 Promotes Proliferation of Endometriotic Stromal Cells via the SLIT2-ROBO1 Axis 12 samples shares proliferation, promotes
- GSE342455 Transcriptomic profiling of tumor-associated macrophages following pharmacological SYK inhibition in a human breast cancer co-culture model 6 samples shares pharmacological, inhibition
- GSE270157 Linker histone variant H1-10 promotes prostate cancer proliferation [ChIP-seq] 22 samples shares proliferation, promotes
- GSE289278 Non-enzymatic SETD1A activity drives breast cancer cell proliferation via cyclin K. 20 samples shares proliferation, activity
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.