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Cultured alveolar basal cells differ in their transcriptome, but display similar characteristics and functional properties to airway basal cells

GSE270495 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/08/19 Platform GPL20301
Summary
Basal cells ectopically appear within the lung parenchyma of interstitial lung disease (ILD) patients, however their exact origin, role and function remain poorly understood. By comparing ectopic alveolar to “classical” airway basal cells, we aimed to get a better understanding of the origin and disease-specific characteristics of alveolar basal cells.
Published in
Characteristics of ectopic alveolar basal cells relative to airway basal cells in fibrosis
Blumer S, Khan P, Roux J et al. · ERJ open research 2025 · PMID 41220820 · doi:10.1183/23120541.01259-2024
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Also filed as BioProject PRJNA1126746. Searching any of these in the dataset finder brings you back here.

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