Effects of deletion Rack7 on gene expression in primary astrocyte during mouse postnatal development [RNA-Seq]
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 6 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- RACK7 Interacts with PRC2 Complex to Regulate Astrocyte DevelopmentAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE270582_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1127524 and SRA study SRP515808. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 6 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8347715 P1-WT-bio rep1 P1-WT
- GSM8347716 P1-WT-bio rep2 P1-WT
- GSM8347717 P1-Rack7-cKO-bio rep1 P1-Rack7-cKO
- GSM8347718 P1-Rack7-cKO-bio rep2 P1-Rack7-cKO
- GSM8347719 P6-WT-bio rep1 P6-WT
- GSM8347720 P6-WT-bio rep2 P6-WT
- GSM8347721 P6-Rack7-cKO-bio rep1 P6-Rack7-cKO
- GSM8347722 P6-Rack7-cKO-bio rep2 P6-Rack7-cKO
- GSM8347723 P8-WT-bio rep1 P8-WT
- GSM8347724 P8-WT-bio rep2 P8-WT
- GSM8347725 P8-Rack7-cKO-bio rep1 P8-Rack7-cKO
- GSM8347726 P8-Rack7-cKO-bio rep2 P8-Rack7-cKO
- GSE99058 Single cell RNA-seq of mouse brain astrocyte transcriptomes 250 samples shares astrocyte, rna-seq
- GSE335221 Effect of keratinocyte-intrinsic VISTA deletion on UV-induced type I interferon and inflammatory gene expression in mouse epidermis [bulk RNA-seq] 28 samples shares deletion, rna-seq
- GSE281738 Single-nuleus RNA-sequencing of septal cells during postnatal development 24 samples shares postnatal, rna-seq
- GSE290989 Charting Postnatal Heart Development Using In Vivo Single-Cell Functional Genomic [snRNA-Seq] 8 samples shares postnatal, rna-seq
- GSE330728 Single-nucleus RNA-seq atlas of 17 ASD-risk mouse lines under early-postnatal fluoxetine or lithium exposure (4-plex On-Chip Multiplexed) 53 samples shares postnatal, rna-seq
- GSE306262 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity [RNA-seq] 40 samples shares astrocyte, rna-seq
- GSE263737 Bi-directional immunosuppressive interactions between astrocytes and glioblastoma cells identified by barcoded viral tracing [Mouse Bulk RNA-Seq Dataset of Monocytes, T Cells and Astrocytes 5OLJ] 33 samples shares astrocyte, rna-seq
- GSE240857 Hmgb2 improves astrocyte to neuron conversion by increasing the chromatin accessibility of genes associated with neuronal maturation in a proneuronal factor-dependent manner[RNA-Seq] 29 samples shares astrocyte, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.